I reviewed the Yamaha O1V96i last year and was impressed with the amount of processing it had to offer, integration with the DAW and real-time DAW plug-in processing via the highly efficient USB audio driver was impressive.
If you are considering a purchase, perhaps this will help you decide - in the UK Yamaha have discounted the RRP of the O1V96i from £2695 to £2095.
With a total of 40 mix channels, 12 channels with XLR and line inputs, two stereo inputs, four stereo FX returns plus 8 ADAT IO each with 4 band EQ, compressor and gate you can mix a lot of inputs. Additionally, there are four assignable Omni output (aux/buss out etc).
USB gives you 16 io which is fully integrated into the routing of the desk and allows you to record multiple channels.
All the Jomox tech and more in the new analog drum machine