We spoke to MOTU today, they have just announced a new ASIO driver for Windows 10 Thunderbolt. Supported interfaces are the 1248, 16A, 112D and the 8M. The new drivers are part of the new Windows 10 support from Microsoft and include re-written USB drivers to decrease round trip latency on both Mac and PC.
The new MOTU Thunderbolt/USB ASIO driver supports all latest-generation MOTU audio interfaces (equipped with AVB/TSN networking) and will be made available to all MOTU users as a free download during Q2, 2016 at www.motu.com/download.